Evidence-graded · Source-cited Peer-reviewer panel · 6 clinicians
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WADA Prohibited

WADA Prohibited is a recurring topic in our peptide coverage. This hub collects every article tagged WADA Prohibited, newest first, each evidence-graded and tied to real, verifiable sources.

Peptide Encyclopedia

Pentadeca Arginate (PDA): Evidence, Mechanism & Legal Status

A clinical monograph on Pentadeca Arginate — the L-arginine salt of BPC-157. No studies exist under the 'PDA' name; the borrowed parent evidence is 35:1 preclinical, with zero human RCTs and an unsettled 2026 legal status.

Peptide Encyclopedia

PEG-MGF: Evidence, Mechanism, Dosing & Legal Status

A clinical monograph on PEG-MGF — the pegylated Mechano Growth Factor E-peptide marketed for muscle repair and recovery. Preclinical-only evidence, no human trials, and a restricted 2026 legal status.

Peptide Encyclopedia

P21 (P021): Evidence, Mechanism & Legal Status

A clinical monograph on P21 (P021, Ac-DGGLAG-NH2) — a small-molecule CNTF mimetic marketed as a nootropic peptide. Reproducible rodent neurogenesis and anti-tau data, but zero human trials and an unapproved-research-chemical status.

Peptide Encyclopedia

N-Acetyl Semax Amidate: Evidence, Mechanism & Legal Status

A clinical monograph on N-Acetyl Semax Amidate — the terminally-stabilized analog of the Russian nootropic Semax. No human or animal data on the modified molecule, an unproven potency story, and an unsettled 2026 legal status.

Peptide Encyclopedia

N-Acetyl Selank Amidate: Evidence, Mechanism & Legal Status

A clinical monograph on N-Acetyl Selank Amidate — a twice-stabilized analog of the Russian anxiolytic peptide Selank. No dedicated human or animal study exists; every claim is extrapolated, placing the analog itself at evidence grade D.

Peptide Encyclopedia

The MOTS-c, Humanin & SHLP Axis: Mitochondrial Peptides Explained

A clinical monograph on the mitochondrial-derived peptide (MDP) axis — MOTS-c, humanin and the small humanin-like peptides (SHLP). One coherent mechanism, three very different maturity tiers, and zero approved human therapies.

Peptide Encyclopedia

MOTS-c: Evidence, Mechanism, Dosing & Legal Status

A clinical monograph on MOTS-c — the 16-amino-acid mitochondrial-derived peptide marketed as an 'exercise mimetic' and metabolic regulator. Striking rodent data, no completed human efficacy trial, and an unsettled 2026 legal status.

Peptide Encyclopedia

MGF (Mechano Growth Factor): Evidence, Mechanism & Status

A clinical monograph on MGF (IGF-1Ec) — the mechanosensitive IGF-1 splice variant marketed for muscle repair and satellite-cell activation. Compelling rodent mechanism, contested preclinical data, zero human trials, and an unsettled 2026 legal and anti-doping status.

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MK-677 (Ibutamoren): Evidence, Mechanism & Legal Status

A clinical monograph on MK-677 (ibutamoren) — the oral, non-peptide ghrelin-receptor agonist that reliably raises GH and IGF-1, yet failed its clinical disease endpoints and carries a congestive-heart-failure safety signal.

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Melanotan II: Evidence, Mechanism, Risks & Legal Status

A clinical monograph on Melanotan II (MT-II) — the non-selective melanocortin agonist sold illegally for tanning. Thin 1990s human data, a high-risk safety profile, and an unapproved 2026 legal status.

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Melanotan I (Afamelanotide): Evidence, Mechanism & Legal Status

A clinical monograph on Melanotan I — INN afamelanotide, marketed as SCENESSE — the only FDA-approved melanocortin agonist, with Grade-A EPP photoprotection data and a separate unapproved gray-market tanning identity.

Peptide Encyclopedia

Larazotide Acetate: Evidence, Mechanism & Legal Status

A clinical monograph on larazotide acetate (AT-1001) — the gut tight-junction regulator developed for celiac disease. Real Phase 2 symptom data, a failed Phase 3, and an unapproved 2026 legal status.

Peptide Encyclopedia

KPV Peptide: Evidence, Mechanism, Dosing & Legal Status

A clinical monograph on KPV — the anti-inflammatory tripeptide fragment of alpha-MSH. Deep rodent and cell-culture data for gut and skin inflammation, zero human trials, and an unsettled 2026 legal status.

Peptide Encyclopedia

Kisspeptin-10: Evidence, Mechanism, Dosing & Legal Status

A clinical monograph on Kisspeptin-10 (KP-10), the KISS1R/GPR54 agonist that drives the reproductive axis. Robust human physiology data, no Grade-A outcome RCT, and a 2026 legal status that is not-approved, non-compoundable and banned in sport.

Peptide Encyclopedia

Ipamorelin: Evidence, Mechanism, Dosing & Legal Status

A clinical monograph on ipamorelin — the selective growth-hormone secretagogue famous for the CJC-1295 stack. One human PD study, one failed RCT, and an unsettled 2026 legal status.

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Tesamorelin/Ipamorelin Stack: Evidence, Mechanism & Status

A clinical monograph on the tesamorelin + ipamorelin stack — a GHRH-analog plus ghrelin-receptor agonist combination marketed for body composition. Sound mechanism, Grade-A component data, but zero RCTs of the combination itself.

Peptide Encyclopedia

Insulin: Evidence, Mechanism, Dosing & Legal Status

A clinical monograph on insulin — the prototype FDA-approved therapeutic peptide. Grade-A human evidence in diabetes, a tyrosine-kinase mechanism, and a stark warning on lethal non-medical 'anabolic' misuse.

Peptide Encyclopedia

IGF-1 LR3: Evidence, Mechanism, Dosing & Legal Status

A clinical monograph on IGF-1 LR3 (Long R3 IGF-1) — the IGFBP-evading, long-acting IGF-1 receptor agonist sold as a lab reagent. Real animal anabolic signal, zero human trials, and serious hypoglycemia and cancer-promotion concerns.

Peptide Encyclopedia

IGF-1 DES (1-3): Evidence, Mechanism, Dosing & Legal Status

A clinical monograph on des(1-3)IGF-I — the truncated, IGFBP-evading IGF-1 analogue marketed for localized muscle growth. Potent in rodents, unproven in humans, and WADA-banned at all times.

Peptide Encyclopedia

Humanin: Evidence, Mechanism, Dosing & Legal Status

A clinical monograph on humanin — the first mitochondrial-derived peptide. Deep preclinical cytoprotection data, intriguing human biomarker correlations, zero interventional human trials, and a real tumor-promotion caveat.

Frequently asked

What is WADA Prohibited?

WADA Prohibited is a topic our editors cover across the site. This hub aggregates the related, evidence-graded guidance.

How often is the WADA Prohibited hub updated?

This hub updates automatically whenever a new article is tagged WADA Prohibited, so the latest coverage appears first.

Are WADA Prohibited claims sourced?

Yes. Every article here grades its efficacy claims A-D and cites real, verifiable studies, regulatory documents or trial registries.

Medical Disclaimer · Read in full

PeptideVox is an evidence reference, not medical advice. Nothing here authorizes you to acquire, possess, or self-administer any compound.

01 · Not FDA-approved

The majority of compounds documented here are not approved by the FDA for human use. Approved drugs (e.g. semaglutide, tirzepatide) are noted explicitly and require a licensed prescriber.

02 · Research chemicals

Many peptides — including BPC-157 and GHK-Cu in injectable form — are sold strictly "for research use only — not for human consumption." Purity, identity, and dosing of such products are not regulated or guaranteed.

03 · WADA-prohibited

Several compounds are banned in competitive sport under the WADA Prohibited List. Athletes risk sanction regardless of intent or formulation.

04 · Consult a clinician

Always consult a qualified, licensed healthcare professional before considering any compound. Individual risk depends on your full medical context.

This content is for informational and educational purposes only · No physician–patient relationship is created · Evidence grades reflect published data as of the stated revision and may change.